Transfusion Transmitted Injuries Surveillance System (TTISS) is a national hemovigilance system implemented by the Public Health Agency of Canada (PHAC) to monitor serious, moderate and selected minor adverse transfusion reactions (ATRs) related to blood components and blood products. The Ministry of Health (MOH) in Ontario and the Public Health Agency of Canada (PHAC) contracts the Michael DeGroote Transfusion Research Program (MCTR) at McMaster University to coordinate the TTISS activities in Ontario, though TTISS-ON is acknowledged to be a leader in hemovigilance in Canada.
The program is designed to capture ATRs related to all blood products comprised of blood components (red cells, plasma, platelets, cryoprecipitate) and blood products (immunoglobulin preparations, coagulation factors, and albumin).
There are 159 hospitals that transfuse blood products in Ontario. This report summarizes ATRs received from all 159 Ontario hospitals that voluntarily participated in the TTISS during the period 2019 – 2023. All TTISS participating hospitals submit reportable ATRs (reportable to PHAC exclude minor allergic, delayed serological and febrile non-hemolytic reactions). Click on the report below to download the full PDF report.
